Functionalization | Hummingbird Scientific

‹ MicroFabrication

Hummingbird Scientific and Dune Sciences

Surface functionalization of membrane window chips can greatly enhance liquid- and gas-cell, as well as other in-situ TEM experiments. Recognizing this, Hummingbird Scientific and Dune Sciences have entered into an exclusive partnership, combining Hummingbird’s specialized liquid and gas cell and other in-situ microscopy holders and chips with Dune Sciences’ full range of surface functionalization products.

Dune Sciences Smart Grids™ Technology

dune-smart-grid Functionalized substrates enhance imaging and analysis in in-situ microscopy. Dune Sciences offers functionalized for nearly any material or assay.

Benefits:

Simplifies sample preparation and improves dispersion/uniformity of coverage.
Eliminates artifacts such as agglomeration from sample preparation
Localizes samples on one membrane to improve image focus and resolution
Isolates/tethers biomolecules and nanomaterials through bifunctional linkers or immunocapture

Applications:

dune-diagram

Environmental transformations of nanomaterials
Immobilization of biological structures on substrates
Dynamic imaging of self-assembly processes
On-grid assays

Surface chemistry options include:

- Silanization/chemical derivatization
- Positive or negative surface charges
- Custom hydrophobic/hydrophilic coatings
- Self-assembled monolayers
- Patterned surface chemistry
- Immunospecific chemistries for purifying/isolating target analytes

STEM Image of 1.5 nm AuMES in water, immobilized on a Hummingbird fluid cell with a positively functionalized surface. (Image taken with a Hummingbird Scientific holder, courtesy of John Miller, Dune Sciences Inc.) — STEM Image of 1.5 nm Au MES in water, immobilized on a Hummingbird fluid cell with a positively-functionalized surface. (Image taken with a Hummingbird Scientific holder, courtesy of John Miller, Dune Sciences Inc.)

Contact Hummingbird Scientific directly for more information.

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